Our most popular product is by far the 6000 mg CBD isolate bottle with no THC.
This goes to the heart of the biggest misconception in the CBD market.
There's so much junk product out there with 250 mg of CBD (if you're lucky) in the entire bottle.
These products are clearly paying zero attention to the research.
We'll explain below but for CBD to really have effects found in research touted by everyone, there are certain levels needed.
Let's cover these topics to explain:
- How much CBD is in the 6000 mg bottles
- Why are higher levels of CBD needed
- The importance of 300 mg CBD per day
- How to save on 6000 mg CBD bottle
Let's get started!
How much CBD is in the 6000 mg bottles
First, in the 30 ml (1 ounce) bottle, there is 6000 mg of CBD isolate.
That's CBD by itself.
Many brands will camouflage this with "cannabinoids", etc.
We specify the level of CBD and it's backed by 3rd party testing which can be found at the top of every page.
The verified level will usually be slightly different than right at 6000 mg but generally, it's higher.
You can multiply the amount shown in the testing by 30 since it's per fluid ml and there are 30 ml in the bottle.
What about the dropper?
Each dropper is 1 ml so each dropper is approximately 200mg of CBD isolate.
The base oil is MCT oil from organic coconut extract.
Just two ingredients.
You don't need all the preservatives (shelf life of 18 months) since both MCT oil and CBD isolate are anti-bacterial and anti-microbial.
200 mg doses per dropper but you can break this up.
There are 4 hash marks on the dropper for ¼, ½, ¾, and 1.
- The ¼ mark would be 50 mg of CBD
- The ½ mark would be 100 mg of CBD
- The ¾ mark would be 150 mg of CBD
A daily dose can be broken up into multiple doses since peak CBD is around 4-6 hours after taking.
So...3 doses after means of ½ a dropper would be 100 mg each or 300 mg for the day.
That specific number matters and we'll cover it below.
First, why is the 6000mg bottle of CBD isolate so popular?
Why are higher levels of CBD needed?
Many brands out there will offer 250 mg bottles of CBD at the same 30ml level.
That's about 8mg per dropper. This is a ridiculously low level and runs counter to everything that the research is based on.
Check our reviews for CBD dosage here.
- Sleep studies point to 160 mg of CBD (see CBD and sleep)
- Anxiety and depression studies run up 300 mg of CBD (CBD and anxiety or CBD and depression)
- More acute and serious research on drug withdrawal or performance anxiety actually were at 600 mg (CBD and addiction or CBD and public speaking)
- Schizophrenia looked at 800 mg of CBD daily (see CBD and schizophrenia)
8mg is not going to cut it. It's well established that a wellness or trial dose is around 30-40mg.
Again, check the research above to learn more. We've written 1 million-plus words of deep dives across topics with 100's of NIH studies reviewed. That's really what we do!
There is a particular area of research that really catches our attention and it's critical to mental health and our nervous system.
Let's go there now.
The importance of 300 mg CBD per day
There's a very important term called neurogenesis.
Literally, it means making a new brains (or nerves technically...neurons).
Think of neurogenesis as the push back again all the insults our brain and nervous system has to deal with:
- Trauma (see CBD and trauma)
- Stress, especially chronic stress
- Injury (see CBD and TBI)
- Drugs and alcohol (see CBD and alcohol)
- Infection and overactive immune response (see CBD and neuroinflammation)
Neurogenesis is strongly driven by a pathway called BDNF (brain-derived neurotrophic factor).
This is essentially our brain's fertilizer!
It's essential to a healthy, functioning brain that grows, changes, and adapts.
Studies on depression really helped us narrow the range of CBD to support this process.
Cannabidiol Induces Rapid and Sustained Antidepressant-Like
Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex
- Anti-depressant effects (see CBD versus SSRIs or CBD and serotonin)
- Increased BDNF
- Prefrontal cortex - a key player in both the depression and anxiety circuit
Here's the catch that matters for the level of CBD.
The neurogenesis effect was found to occur in a bell curve.
It increases with increasing CBD dose until around 300 mg and then it starts to go down as other pathways kick in.
This speaks to the longer-term effects of CBD to replenish, rebuild, and rewire (key to addiction).
For that reason, 300 mg daily is a key target point for many people once they read the research.
So...more than half a bottle of 250mg CBD. See the issue?
Given that, are there ways to reduce the cost and get these levels born out by research?
How to save on 6000 mg CBD bottle
First, the practical fixes.
Hold the CBD oil under your tongue for up to 60 seconds. This bypasses the liver/gut and can boost both speed and bioavailability to the bloodstream via the sublingual gland.
Take after meals ideally. Again, the liver is busy with fats from our meal and more CBD can get through and for longer periods of time.
We price our 6000mg bottle at 2-3 cents per mg of CBD already. Lowest on the market we find.
Again, we found CBD as the result of a brutal perimenopause (that story is here) so we're well versed with trauma.
Due to that, we offer different ways to save up to 50% including subscriptions, reviews, referrals, and large discounts throughout the year.
It's the only way to make this viable for many people and we've seen firsthand how adequate levels of quality CBD can really help.
Our 6000mg bottle also meets the following:
- From organically grown US hemp at an FDA registered farm
- 3rd party tested
- Zero THC (see CBD versus THC -very important)
- No solvents
- No heavy metals
- No pesticides
- No bacteria
- No mold
Again, our testing is available at the top of every page.
We focus on CBD isolate because...that's what the research is based on!
More importantly, 40-60% of the population has histamine issues which increase as we get older and for women (thanks for leaving, progesterone).
All the plant material in full-spectrum (not to mention the small amount of THC allowed) can have very different side effects than CBD isolate.
We learned this the hard way when first exploring CBD.
Always work with a doctor or naturopath with any supplement!
The information provided here is not intended to treat an illness or substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider.